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IMAGES

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    hozumi and tonegawa experiment

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  4. Organization and expression of Ig genes

    hozumi and tonegawa experiment

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VIDEO

  1. How I define creativity: Susumu Tonegawa

  2. Susumu Tonegawa, Nobel Prize in Medicine 1987: How I define creativity

  3. A Conversation with Susumu Tonegawa

  4. Controlling the brain with light to reactivate lost memories

  5. Tonegawa's (De)Motivational Speech (from Kaiji)

  6. Photo electric effect & failure of wave theory

COMMENTS

  1. Evidence for somatic rearrangement of immunoglobulin genes …

    N Hozumi, S Tonegawa. PMID: 824647. PMCID: PMC431171. DOI: 10.1073/pnas.73.10.3628. Abstract. A high-molecular-weight DNA from Balb/c mouse early embryo or from MOPC 321 …

  2. SOMATIC GENERATION OF IMMUNE DIVERSITY

    SOMATIC GENERATION OF IMMUNE DIVERSITY. Nobel lecture, December 8, 1987. by. SUSUMU TONEGAWA. Center for Cancer Research and Department of Biology, …

  3. The Nobel Chronicles

    Using new techniques, Tonegawa and Nobumichi Hozumi tested the latter theory. They used cloned DNA from myeloma cells and DNA from mouse embryo and found that, in the embryonic DNA, the constant and …

  4. Evidence for somatic rearrangement of immunoglobulin genes …

    N Hozumi 1 , S Tonegawa. Affiliation. 1 Basel Institute for Immunology, Switzerland. PMID: 15383553. Publication types. Biography. Classical Article. Historical Article. MeSH …

  5. Chapter 23: Immunology

    The generation of antibody diversity was a problem awaiting the development of powerful molecular techniques. Tonegawa went on to clone V-region genes and prove that the rearrangement must occur somatically. These findings affected …

  6. Milestone 10: Building antibody diversity

    In 1976, a key paper by Hozumi and Tonegawa provided experimental evidence for the somatic rearrange-ment of immunoglobulin genes.

  7. That Great Time in Basel Commentary

    the Hozumi and Tonegawa experiment (Tonegawa et al., 1977a). This marked the beginning of a series of truly exciting discoveries that came out of our collaboration during the subsequent …